◀ Back to IL1B

GAPDH — IL1B

Text-mined interactions from Literome

Yego et al., Invest Ophthalmol Vis Sci 2009 : With use of the transformed rat Müller cell line ( rMC-1 ) and isolated human Müller cells ( HMCs ), the authors examined the effect of high glucose ( 25 mM ), IL-1beta , TNFalpha, IL-6, and high glucose ( 25 mM ) plus inhibitors of the caspase-1/IL-1beta signaling pathway on GAPDH nuclear accumulation, which was evaluated by immunofluorescence analysis ... Further, high glucose induced GAPDH nuclear accumulation in Müller cells was mediated by IL-1beta ... In contrast, IL-6 ( 2 ng/mL ) had a strong protective effect attenuating high glucose and IL-1beta induced GAPDH nuclear accumulation in Müller cells
Dimmeler et al., J Immunol 1993 (Insulinoma) : IL-1 beta ( 10 ( -9 ) M ) inhibited GAPDH activity about 55 %, compared with control values