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MYLIP — PTPN1

Text-mined interactions from Literome

Liu et al., BMC systems biology 2010 (Anoxia...) : For instance, loss of miR-149, miR-200c and mir-141 causes gain of function of oncogenes ( KCNMA1, LOX ), VEGFA and SEMA6A respectively and increased levels of miR-142-3p, miR-185, mir-34a, miR-224, miR-21 cause loss of function of tumor suppressors LRRC2, PTPN13 , SFRP1, ERBB4, and ( SLC12A1, TCF21 ) respectively
Yang et al., Hepatology 2012 (Insulin Resistance) : Experiments using miR-122 mimic and its inhibitor indicated that miR-122 repression caused PTP1B induction ... The regulatory role of JNK1 in PTP1B induction by a decrease in miR-122 level was strengthened by cell based assays using isoliquiritigenin and liquiritigenin ( components in Glycyrrhizae radix ) as functional JNK inhibitors ; JNK inhibition enabled cells to restore IR and IRS1/2 tyrosine phosphorylation and insulin signaling against tumor necrosis factor alpha, and prevented PTP1B induction