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HNRNPH1 — IFNB1

Text-mined interactions from Literome

Huang et al., Cytokine 2001 : IFN-beta dose-dependently increased IL-3Ralpha+ DCs and decreased CD1a+ DCs
Liu et al., J Immunol 2001 : The up-regulation of TRAIL on IFN-beta stimulated DCs partially contributed to the increased cytotoxicity of DCS : Pretreatment of TRAIL-sensitive tumor cells with caspase-3 inhibitor could significantly increase their resistance to the cytotoxicity of IFN-beta stimulated DCS : In contrast, NF-kappaB inhibitor could significantly increase the sensitivity of tumor cells to the killing by nonstimulated or LPS stimulated DCS : Our studies demonstrate that IFN-beta stimulated DCs are functionally cytotoxic
Huang et al., Clin Exp Immunol 2001 (Multiple Sclerosis) : IFN-beta and IL-10 inhibited the costimulatory capacity of DCs in mixed lymphocyte reaction (MLR) and showed additive effects on suppression of IL-12 production by DCs
Vidalain et al., J Immunol 2001 : However, IFN-alpha- or IFN-gamma stimulated CD11c+ blood DCs and IFN-beta stimulated monocyte derived DCs were recently reported to express functional TNF related apoptosis inducing ligand ( TRAIL ), suggesting that DCs may become cytotoxic effector cells of innate immunity upon appropriate stimulation
Wiesemann et al., J Neuroimmunol 2002 : The effects of interferon beta (IFN-beta) , an immunomodulatory cytokine used in multiple sclerosis (MS) therapy, on DCs are not well understood ... Moreover, IFN-beta enhanced the capacity of DCs to stimulate autologous T-cells to secrete IL-13, IL-10 and IL-5
Kaiser et al., J Exp Med 2009 : In contrast, CpG induction of both IFN-alpha and IFN-beta by plasmacytoid DCs was decreased in the absence of TPL-2, although extracellular signal regulated kinase ( ERK ) activation was blocked
Ramgolam et al., J Immunol 2009 (Multiple Sclerosis) : We have investigated the effect of IFN-beta-1a on dendritic cells (DCs) and naive CD4 ( + ) CD45RA ( + ) T cells derived from untreated MS patients and healthy controls in the context of Th17 cell differentiation
Yen et al., J Immunol 2010 : In vivo treatment with IFN-beta results in lower numbers of DCs migrating to the draining lymph node following exposure to FITC and in reduced expression of CCR7 and MMP-9 in splenic CD11c ( + ) DCs following LPS administration
Hoshino et al., J Immunol 2010 : In this study, we showed that IKKalpha was required for production of IFN-beta , but not of proinflammatory cytokines, by TLR7/9 stimulated conventional DCs