◀ Back to AKT1

AKT1 — SLC8A1

Text-mined interactions from Literome

Formisano et al., Mol Pharmacol 2008 : Indeed, the doxycycline dependent overexpression of constitutively active Akt1 in tetracycline ( Tet ) -Off PC-12 positive mutants and the exposure of Tet-Off PC-12 wild type to nerve growth factor induced an up-regulation of NCX1 and NCX3 proteins ... NCX1 up-regulation induced by Akt1 activation occurred at the transcriptional level because NCX1 mRNA increased, and it was counteracted by cAMP response element binding protein 1 inhibition through small interfering RNA strategy
Pignataro et al., Adv Exp Med Biol 2013 (MAP Kinase Signaling System...) : ( 3 ) NCX1 upregulation and NCX3 upregulation are mediated by p-AKT since its inhibition reverted the neuroprotective effect of preconditioning and postconditioning and prevented NCXs overexpression