Gene interactions and pathways from curated databases and text-mining

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CD40 — CXCL10

Text-mined interactions from Literome

Vockerodt et al., Int J Cancer 2005 (Lymphoma) : Transcriptional activation of IP-10 by LMP1 or CD40 stimulation depends on an NF-kappaB motif within the proximal 435 bp fragment
D'Aversa et al., J Neurosci Res 2008 (AIDS Dementia Complex...) : CD40-CD40 ligand interactions in human microglia induce CXCL8 ( interleukin-8 ) secretion by a mechanism dependent on activation of ERK1/2 and nuclear translocation of nuclear factor-kappaB (NFkappaB) and activator protein-1 (AP-1)
Singh et al., J Interferon Cytokine Res 2008 (Colitis...) : Ex vivo antigen and CXCL10 stimulation of mucosal cells caused an increase in MHC class II, CD40 , and CD86 as well as a decrease in CD30 ligand (CD30L) expression by DCs