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CCL2 — TP53

Text-mined interactions from Literome

Hacke et al., Molecular cancer 2010 (Cell Transformation, Neoplastic) : A general physiological role of p53 in MCP-1 regulation was further substantiated in HPV negative cells harboring a temperature-sensitive mutant of p53 and in Li-Fraumeni cells, carrying a germ-line mutation of p53 ... In both cases, non-functional p53 leads to diminished MCP-1 transcription upon TNF-alpha treatment
Shimizu et al., Life Sci 2012 : An antioxidant, and inhibitors of NF-?B, p53 , ERK pathway ( MEK1/2 ), and JNK suppressed indoxyl sulfate induced mRNA expression of MCP-1 in HK-2 cells
Tang et al., Curr Mol Med 2012 : We are therefore interested in how p53 regulates CCL2 gene expression ... CCL2 production induced by lentiCLG in human monocytes or mouse primary macrophages was blocked in the presence of p53pep170