Gene interactions and pathways from curated databases and text-mining

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HMOX1 — MPO

Text-mined interactions from Literome

Maeshima et al., Biochem Pharmacol 2005 (Respiratory Distress Syndrome, Adult...) : HA pretreatment markedly induced HO-1 in pulmonary epithelial cells, and ameliorated the lung injury induced by HSR as judged by the improvement of histological changes, while it decreased TNF-alpha and inducible nitric oxide synthase gene expression, lung wet weight to dry weight ratio, and myeloperoxidase activity
Collino et al., Dis Model Mech 2013 (Disease Models, Animal...) : Besides, chronic HO-1 activation suppressed the elevated levels of myeloperoxidase (MPO) activity, interleukin 1ß (IL-1ß) production and tumor necrosis factor-a (TNFa) production that were evoked by the ischemic injury, and increased the plasma level of the anti-inflammatory cytokine IL-10