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MMP9 — MYLIP

Text-mined interactions from Literome

Wang et al., Oncogene 2010 (Carcinoma, Hepatocellular...) : Ectopic expression and depletion of miR-181b showed that miR-181b enhanced matrix metallopeptidases (MMP)2 and MMP9 activity and promoted growth, clonogenic survival, migration and invasion of hepatocellular carcinoma ( HCC ) cells that could be reversed by modulating TIMP3 level
Stanczyk et al., Arthritis Rheum 2011 (Arthritis, Rheumatoid...) : Previously, we described increased expression of miR-155 and miR-146a in rheumatoid arthritis ( RA ) and showed a repressive effect of miR-155 on matrix metalloproteinase ( MMP ) expression in RA synovial fibroblasts ( RASFs )
Liu et al., J Cell Physiol 2012 : In conclusion, miR-520c and miR-373 increased the expression of MMP9 by directly targeting the 3'-UTRs of mRNAs of mTOR and SIRT1 and suppressing their translation ; resulting in activation of the Ras/Raf/MEK/Erk signaling pathway and NF-?B ; and, finally, increasing the mRNA, protein, and activity of MMP9 and enhancing cell migration and cell growth in 3D type I collagen gels
Jones et al., Circulation. Cardiovascular genetics 2011 (Aortic Aneurysm, Thoracic) : MMP-2 and MMP-9 were identified as potential targets for miR-29a and miR-133a , respectively, and MMP-2 was subsequently verified as a miR-29a target in vitro
Wu et al., Chin Med J (Engl) 2011 (Glioblastoma) : In addition, miR-7 repressed p-ERK1/2 and p-AKT level, MMP-2 and MMP-9 expression
Iizuka et al., Fibrogenesis & tissue repair 2012 : The overexpression of miR-214-5p in LX-2 cells increased the expression of fibrosis related genes, such as matrix metalloproteinase (MMP)-2, MMP-9 , a-smooth muscle actin, and transforming growth factor ( TGF ) -ß1
Asuthkar et al., Oncotarget 2012 (Brain Neoplasms...) : We also investigated whether miR-211 is involved in the regulation of MMP-9 and thus plays a functional role in GBM
Chiang et al., Biochim Biophys Acta 2013 (Breast Neoplasms...) : Anti-miR-182 increased the MMP inhibitor RECK protein in MDA-MB-231 cells while pre-miR-182 reduced RECK protein but not mRNA in normal mammary epithelial H184B5F5/M10 cells
Zhou et al., Liver Int 2013 (Carcinoma, Hepatocellular...) : Our results suggest that miR-491 is involved in metastasis of HCC by blocking EMT and decreasing MMP-9 levels, which may provide a new clue for preventing tumour metastasis of HCC
Guo et al., Oncol Rep 2013 : Furthermore, the overexpression of miR-708 reduced the expression of Akt1, CCND1, MMP2 , EZH2, Parp-1 and Bcl2 in A172 and T98G cells
Lin et al., Br J Cancer 2013 (Lung Neoplasms...) : Anti-miR-92a attenuates MMP activity, migration and invasion of H1299 cells and STAT3 overexpressing H460 cells, suggesting miR-92a is critical for STAT3 induced invasiveness.Conclusion : The STAT3 induced miR-92a promotes cancer invasion by suppressing RECK and targeting of the STAT3/miR-92a axis may be helpful for cancer treatment
Jin et al., Asian Pac J Cancer Prev 2013 (Bone Neoplasms...) : This was confirmed by western blotting, which showed that miR-218 expression inhibited TIAM1, MMP2 and MMP9 protein expression