Gene interactions and pathways from curated databases and text-mining

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BDNF — FOS

Text-mined interactions from Literome

Ruiz-León et al., J Neurochem 2001 (Neuroblastoma) : These results suggest that activation of the APP promoter by BDNF is largely independent of PKC and AP-1
Zhang et al., Nat Genet 2002 : Moreover, c-Fos regulates the expression of the kainic acid receptor GluR6 and brain derived neurotrophic factor (BDNF) , both in vivo and in vitro
Calella et al., Neural development 2007 : Genetic depletion of Trk receptors led to impaired recruitment of C/EBPs and NeuroD in vivo, and elimination of Cebpa and Cebpb alleles reduced BDNF induction of Fos , Egr1 and Egr2 in primary neurons
Zhang et al., J Huazhong Univ Sci Technolog Med Sci 2007 (Cerebral Infarction...) : The positive expression of c-Fos and BDNF was detected in the cortex surrounding the infarction areas, while the expression of c-Fos and BDNF increased significantly in TMS treatment group in comparison with those in model group 7, 14, 21, and 28 days ( P < 0.05 ) and 7, 14, 21 days ( P < 0.01 ) after infarction, respectively
Cohen et al., Proc Natl Acad Sci U S A 2011 (Calcium Signaling...) : Intriguingly, the activity of TrkB, the BDNF receptor, is required in the cell body for the induction of Arc and c-Fos mediated by dendritically applied BDNF
Kuzniewska et al., Mol Cell Biol 2013 : BDNF stimulation of neurons induced binding of endogenous c-Fos to the proximal MMP-9 promoter region
Nakagawara et al., Mol Cell Biol 1994 (Neuroblastoma) : BDNF also induces expression of the immediate-early genes c-FOS and NGFI-A but not NGFI-B or NGFI-C
Sano et al., Biochem Biophys Res Commun 1996 : These results indicate that nascent AP-1 is not required for the activation of BDNF gene, leading to the notion that the BDNF gene can be activated by Ca2+ signals as an immediate early gene
Courtney et al., J Neurosci 1997 : The cells express TrkB protein and show elevated c-Fos and c-Jun levels in response to BDNF
Coffey et al., Neurosci Lett 1997 : We find that BDNF but not NGF rapidly ( within 2 h ) upregulates levels of synaptophysin, tau and c-Fos correlating with expression of the neurotrophin receptor TrkB
Hsieh et al., Exp Neurol 1998 (Body Weight...) : BDNF restores the expression of Jun and Fos inducible transcription factors in the rat brain following repetitive electroconvulsive seizures