Gene interactions and pathways from curated databases and text-mining

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ABL1 — BCL2

Text-mined interactions from Literome

Horita et al., J Exp Med 2000 (Blast Crisis...) : Here, we show that the interleukin 3-independent expression of the antiapoptotic protein, Bcl-xL , is induced by Bcr-Abl through activation of signal transducer and activator of transcription ( Stat ) 5
Keeshan et al., Leukemia 2001 : Despite the drug-resistant phenotype, high Bcr-Abl levels concomitantly increased the expression of p53, p21, Bax and down-regulated Bcl-2
Sánchez-García et al., J Mol Biol 1997 (Cell Transformation, Neoplastic...) : Regulation of Bcl-2 gene expression by BCR-ABL is mediated by Ras
Chen et al., Oncogene 1997 : Here we demonstrate that v-Abl PTK activation is followed by an approximately twofold increase in mRNA level of Bcl-XL by 6 h and a corresponding increase in Bcl-XL protein level by 24 h. Bcl-xL RNA and protein decreased in IL-3 deprived cells in the absence of v-Abl PTK activity