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Text-mined interactions from Literome

Gorelik et al., J Immunol 2004 : Herein we demonstrate that B cell activating factor of the TNF family ( BAFF ), a B cell survival factor, also regulates CD21/35 and CD23 expression ... BAFF blockade in wild-type mice down-modulates CD21/35 and CD23 on B cells while survival remains intact, and BAFF exposure causes elevated CD21/35 and CD23 expression
Mongini et al., J Immunol 2005 : The synergy was observed over a wide range of BCR : ligand affinities and involved : 1 ) cooperative effects at promoting early cell cycle progression and viability ; 2 ) BCR : CD21 coligation promoted increases in BAFF receptors that were highly regulated by IL-4 ; 3 ) reciprocal effects of IL-4 and BAFF at dampening daughter cell apoptosis typical of stimulation by BCR : CD21 and either cytokine alone ; and 4 ) BAFF sustained expression of antiapoptotic Mcl-1 within replicating lymphoblasts
Debnath et al., Mol Immunol 2007 : Analysis of the regulatory role of BAFF in controlling the expression of CD21 and CD23 ... A key question we address in this report is if BAFF signaling directly induces CD21 and CD23 gene transcription and expression at this B cell transition point, or if their expression is simply coincident with B cell maturation and differentiation ... We present data that supports the contention that BAFF does not preferentially induce the expression of CD23 or CD21 at the T1 to T2 transition, nor does exogenous BAFF lead to preferential increased expression of these proteins/genes in mature B cell populations