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GHRH — IL1B
Text-mined interactions from Literome
De et al., Brain Res 2002
:
In this study, we found both
GHRH ( 100 nM ) and
IL1beta ( 1.2 pM ) acutely
increased cytosolic Ca ( 2+ ) in 7.6 and 4.0 % of cultured hypothalamic neurons tested, respectively, and 1.2 % of neurons responded to both
Taishi et al., J Neuroendocrinol 2004
:
Interleukin-1beta stimulates
growth hormone releasing hormone receptor mRNA expression in the rat hypothalamus in vitro and in vivo ... Up-regulation of hypothalamic GHRH-R by IL-1beta may explain previous findings suggesting that
IL-1beta stimulates
GHRH activity