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PRKACG — RHO

Text-mined interactions from Literome

Spurzem et al., Am J Physiol Lung Cell Mol Physiol 2002 : Augmentation of PKA activity reduced the levels of active Rho and the formation of focal adhesions
Endou et al., Am J Physiol Lung Cell Mol Physiol 2004 : To clarify whether cyclic AMP ( cAMP ) /cAMP dependent protein kinase (PKA) activation and Rho-kinase inhibition share a common mechanism to decrease the Ca2+ sensitivity of airway smooth muscle contraction, we examined the effects of 8-bromoadenosine 3',5'-cyclic monophosphate ( 8-BrcAMP ), a stable cAMP analog, and ( + ) - ( R ) -trans-4- ( 1-aminoethyl ) -N- ( 4-pyridyl ) cyclohexane carboxamide dihydrochloride, monohydrate ( Y-27632 ), a Rho-kinase inhibitor, on carbachol ( CCh ) -, guanosine 5'-O- ( 3-thiotriphosphate ) ( GTPgammaS ) -, 4beta-phorbol 12,13-dibutyrate ( PDBu ) -, and leukotriene D4 ( LTD4 ) -induced Ca2+ sensitization in alpha-toxin permeabilized rabbit tracheal and human bronchial smooth muscle
Sanada et al., Circulation 2004 (Myocardial Infarction) : We examined the effect on Rho-kinase activity during sustained ischemia and infarct size of ( 1 ) preischemic transient coronary occlusion ( IP ), ( 2 ) preischemic activation of PKA/PKC , ( 3 ) inhibition of PKA/PKC during IP, and ( 4 ) inhibition of Rho-kinase or actin cytoskeletal deactivation during myocardial ischemia ... IP and preischemic PKA activation, but not PKC activation, caused a substantial decrease of Rho-kinase activation during sustained ischemia
Yu et al., J Neurosci Res 2007 : Together, the data suggest that MAPK and PKA regulate rhodopsin transcription through parallel signal transduction pathways
Shen et al., J Biol Chem 2008 : cAMP/PKA activation and the downstream Rho inhibition are possible mechanisms by which myocilin in overabundance may lead to TM cell or tissue damage
Lin et al., J Biomed Sci 2012 : We further showed that the capt/ssh mutant phenotypes depended on the inactivation of protein kinase A (PKA) and activation of Rho