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HDAC4 — PPP2R1A

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: PPP2R1A — HDAC4 (physical association, affinity chromatography technology) Li et al., Nat Med 2012*

Text-mined interactions from Literome

Paroni et al., Mol Biol Cell 2008 : PP2A regulates HDAC4 nuclear import ... HDAC4 is dephosphorylated by PP2A and experiments using okadaic acid or RNA interference have revealed that PP2A controls HDAC4 nuclear import ... These observations suggest that PP2A , via the dephosphorylation of multiple serines including the 14-3-3 binding sites and serine 298, controls HDAC4 nuclear import
Li et al., Nat Med 2012 (Ataxia Telangiectasia...) : In ATM deficiency, enhanced PP2A activity leads to HDAC4 dephosphorylation and the nuclear accumulation of HDAC4