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CTSD — TP53
Text-mined interactions from Literome
Sun et al., Mol Carcinog 1999
(Neoplasm Metastasis) :
p53 transcriptionally
activates expression of the genes encoding epidermal growth factor receptor, matrix metalloproteinase (MMP)-2,
cathepsin D , and thrombospondin-1 but represses expression of the genes encoding basic fibroblast growth factor and multidrug resistance-1
Iacobuzio-Donahue et al., Int J Oncol 2004
(Colorectal Neoplasms...) :
However, differential regulation of cathepsin D expression by mutant versus wild-type
p53 may also
contribute to variable
cathepsin D levels in colorectal cancers
Charpin et al., Hum Pathol 1995
(Breast Neoplasms) :
The
p53 tumor expression was
independent of patient age, tumor size, axillary lymph node status, HER-2/neu and
cathepsin D expression, and nuclear morphometric parameters