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NF2 — RAC2

Text-mined interactions from Literome

Wei et al., J Virol 2005 : Merlin , a cellular substrate of PAK2, is homologous to the ezrin-radixin-moesin family and plays a critical role in Rac signaling
Nakai et al., J Neurosci 2006 : NF2 is involved in suppression of Rac signaling, and cultured schwannoma cells contain elevated, GTP bound, active Rac
Huang et al., Oncogene 2008 (Neurilemmoma...) : Consistently, VprBP depletion abolished the in vivo interaction of Merlin and Roc1-Cullin4A-DDB1, which resulted in Merlin stabilization and inhibited ERK and Rac activation