Gene interactions and pathways from curated databases and text-mining

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ECM2 — FOS

Text-mined interactions from Literome

Ahn et al., Gene Ther 2004 (Diabetic Nephropathies) : This investigation was undertaken to test the hypothesis that AP-1 plays an important role in ECM gene expression, and to develop a molecular therapeutic strategy based on decoy oligodeoxynucleotides ( ODN )
Hao et al., Zhonghua Er Ke Za Zhi 2007 : LPS could induce increased secretion of the ECM, including LN, FN, ColIV ; FOS could inhibit the secretion of ECM in GMC in a dose dependent manner at mRNA and protein levels
Lake et al., Biomaterials 2013 : Results from transfection of CAT/a5-promoter plasmids, Western blot and EMSA analyses indicated that ECM/35d significantly increase expression of a5 in HCECs as a result of alteration in the expression and DNA binding of the transcription factors NFI, Sp1, AP-1 and PAX6