Gene interactions and pathways from curated databases and text-mining

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HMGB3 — MOK

Text-mined interactions from Literome

Orlova et al., EMBO J 2007 (Inflammation) : In vitro, HMGB1 enhanced the interaction between Mac-1 and RAGE ... Consistently, HMGB1 activated Mac-1 as well as Mac-1 mediated adhesive and migratory functions of neutrophils in a RAGE dependent manner ... Moreover, HMGB1 induced activation of nuclear factor-kappaB in neutrophils required both Mac-1 and RAGE
Wu et al., Mol Cell Biochem 2013 : Furthermore, HMGB1 induced RAGE protein expression, JNK and NF-?B activation were attenuated by the pretreatment with RAGE-Ab or JNK inhibitor SP600125 in Western blot analysis