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HMGB3 — MOK
Text-mined interactions from Literome
Orlova et al., EMBO J 2007
(Inflammation) :
In vitro,
HMGB1 enhanced the interaction between Mac-1 and
RAGE ... Consistently,
HMGB1 activated Mac-1 as well as Mac-1 mediated adhesive and migratory functions of neutrophils in a
RAGE dependent manner ... Moreover,
HMGB1 induced activation of nuclear factor-kappaB in neutrophils
required both Mac-1 and
RAGE
Wu et al., Mol Cell Biochem 2013
:
Furthermore,
HMGB1 induced
RAGE protein expression, JNK and NF-?B activation were attenuated by the pretreatment with RAGE-Ab or JNK inhibitor SP600125 in Western blot analysis