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HOXC8 — SMAD1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: HOXC8 — SMAD1 (physical association, affinity chromatography technology) Shi et al., J Biol Chem 1999*
• IRef Biogrid Interaction: HOXC8 — SMAD1 (direct interaction, pull down) Shi et al., J Biol Chem 1999*
• IRef Biogrid Interaction: HOXC8 — SMAD1 (direct interaction, two hybrid) Shi et al., J Biol Chem 1999*
• IRef Hprd Interaction: HOXC8 — SMAD1 (in vivo) Shi et al., J Biol Chem 1999*, Wan et al., J Biol Chem 2001*
• IRef Hprd Interaction: HOXC8 — SMAD1 (two hybrid) Shi et al., J Biol Chem 1999*, Wan et al., J Biol Chem 2001*
• IRef Hprd Interaction: HOXC8 — SMAD1 (in vitro) Shi et al., J Biol Chem 1999*, Wan et al., J Biol Chem 2001*
• IRef Ophid Interaction: HOXC8 — SMAD1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Shi et al., J Biol Chem 1999 : Interestingly, purified Smad1 inhibited Hoxc-8 binding to the osteopontin Hoxc-8 site in a concentration dependent manner
Bai et al., J Biol Chem 2000 : More importantly, the Smad6-Hoxc-8 complex inhibits interaction of Smad1 with Hoxc-8- and Smad1 induced transcription activity