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GATA1 — RUNX1

Text-mined interactions from Literome

Chan et al., Blood 2005 (Myelodysplastic Syndromes...) : AML1-FOG2 , which fuses the DNA binding domain of AML1 to most of FOG2, represses the transcriptional activity of both CBF and GATA1
Asou et al., Blood 2007 (Cell Transformation, Neoplastic...) : AML1-TRPS1 stimulated proliferation of hematopoietic colony forming cells and repressed the transcriptional activity of AML1 and GATA-1 by 2 different mechanisms : competition at their cognate DNA binding sites and physical sequestrations of AML1 and GATA-1, suggesting that simultaneous deregulation of AML1 and GATA factors constitutes a basis for leukemogenesis