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EPHB2 — NFATC1
Text-mined interactions from Literome
Chen et al., J Exp Med 2003
:
We show that in stimulated CD4+ T cells, TGF-beta inhibits phosphorylation and activation of the Tec kinase Itk, increase in intracellular Ca2+ levels,
NFATc translocation, and
activation of the mitogen activated protein kinase
ERK that together regulate T cell differentiation
Park et al., Biochem Pharmacol 2008
(Bone Resorption) :
In conclusion, bavachalcone inhibits osteoclastogenesis by interfering with the
ERK and Akt signaling pathways and the
induction of c-Fos and
NFATc1 during differentiation
Kalliolias et al., Arthritis Rheum 2010
(Arthritis, Rheumatoid...) :
IL-27 inhibited human osteoclastogenesis, suppressed the induction of
NFATc1 , down-regulated the expression of RANK and triggering receptor expressed on myeloid cells 2 ( TREM-2 ), and
inhibited RANKL mediated activation of
ERK , p38, and NF-kappaB in osteoclast precursors