Gene interactions and pathways from curated databases and text-mining

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CD28 — CD69

Text-mined interactions from Literome

Villalba et al., Immunity 2000 : Here, we report that PKCtheta function was selectively required in a Vav signaling pathway that mediates the TCR/CD28 induced activation of JNK and the IL-2 gene and the upregulation of CD69 expression
Elias et al., J Immunol 2005 (Malaria...) : Production of IFN-gamma ; up-regulation of CD69 , CD40L, CD95 ( Fas ), and CD95L ( Fas ligand ) ; and induction of apoptosis were also affected by the lack of CD28
Vandenberghe et al., Immunology 1993 : Cross linking of CD5 or CD28 induces an early rise of cytoplasmic free calcium concentration ( [ Ca2+ ) ] i ) and both this rise and CD69 expression were inhibited by chelation of extracellular Ca2+ with ethyleneglycol-bis- ( 2-aminoethyl ) -tetraacetate ( EGTA )