Wiethe et al., J Immunol 2003
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4-1BBL expression up-regulated CD80 and CD86 second signaling molecules in DCs Youlin et al., Yonsei Med J 2010
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The results indicated the recombinant mouse 4-1BBL can effectively activate DCs Weng et al., Braz J Med Biol Res 2011
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Our aim was to construct a recombinant adenovirus co-expressing truncated human prostate-specific membrane antigen ( tPSMA ) and mouse 4-1BBL genes and to determine its effect on dendritic cells (DCs) generated from bone marrow suspensions harvested from C57BL/6 mice for which the effect of 4-1BBL on DCs is not clear, especially during DCs processing tumor associated antigen