Gene interactions and pathways from curated databases and text-mining

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CYP1A2 — FOS

Text-mined interactions from Literome

Chung et al., Arch Pharm Res 2002 (Carcinoma, Hepatocellular) : To elucidate the role of AP-1 in CYP1A2 regulation, we transiently overexpressed c-Jun and c-Fos transcription factors in human hepatoma HepG2 cells, and examined their influence on the CYP1A2 promoter activity by reporter gene assays ... Therefore, it is unlikely that the c-Jun and the c-Fos activate the CYP1A2 promoter through this AP-1 consensus-like sequence in the PRB region
Thomas et al., Toxicol Appl Pharmacol 1998 (Drug-Induced Liver Injury, Chronic...) : Due to the role of Activator Protein-1 (AP-1) in rGSTP1-1 expression and CYP 1A2 in the pathogenesis of porphyria cutanea tarda, immunohistochemical localization of c-jun, c-fos, and CYP 1A2 was also performed