Gene interactions and pathways from curated databases and text-mining

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CEBPE — MYC

Text-mined interactions from Literome

Gery et al., Blood 2004 : Finally, overexpression of C/EBPepsilon in human myeloid cells leads to down-regulation of c-Myc
Cai et al., Chin J Cancer 2006 : This study was to detect the cell-specific expression of C/EBPepsilon, and to investigate the effect of C/EBPepsilon overexpression on c-Myc expression, cell cycle distribution, and cell differentiation of human myelomonocytic leukemia cell line U-937
Matsushita et al., Oncogene 2008 (Leukemia, Myeloid, Acute) : These findings suggest that the ectopic expression of C/EBPepsilon , as well as C/EBPalpha, can induce the monocytic differentiation of myelomonocytic leukemic cells with MLL-fusion gene through the downregulation of Myc , thus providing insight into the development of novel therapeutic approaches