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VEGFA — ZFP57
Text-mined interactions from Literome
Rebar et al., Nat Med 2002
:
In addition, the neovasculature resulting from
ZFP induced expression of
Vegfa was not hyperpermeable as was that produced by expression of murine Vegfa ( 164 ) cDNA
Yu et al., FASEB J 2006
(Ischemia) :
These data demonstrate that
activation of the endogenous
VEGFa gene by an engineered
ZFP can induce angiogenesis in a clinically relevant model and further document the feasibility of designing ZFPs to therapeutically regulate gene expression in vivo
Price et al., Diabetes 2006
(Diabetes Mellitus, Experimental...) :
We show here that this engineered
ZFP-TF activates
VEGF-A in appropriate cells in culture and that the secreted VEGF-A protein induced by the ZFP protects neuroblastoma cell lines from a serum starvation insult in vitro
Li-Shan et al., Chin Med Sci J 2012
:
The ZFP-ATF DNA sequences were located the multiclone sites of PVAX1 vector between the site of BamH1and Xhol.Western blot result showed VEGF expression in EY.HY926 endothelial cells transfected with ZFP-ATF plasmid was significantly higher than that in cells transfected with VEGF165 ( 19.95±3.95 vs.12.15±1.55 µg÷µL, P < 0.01 ) .RT-PCR result showed
VEGF-A mRNA expression level
induced by
ZFP-ATF was high than that induced by VEGF165