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CD8A — IFIH1

Text-mined interactions from Literome

Wang et al., J Immunol 2010 : Although it is known that TLR3 is required for cross priming of CD8 T cells specific for viral Ags, the role of MDA5 in inducing CD8 T cell responses is still unclear
Wang et al., Cell Host Microbe 2012 (Disease Models, Animal...) : In the absence of MDA5, CD8 ( + ) T cell responses to acute infection rely on CD4 ( + ) T cell help, and loss of both CD4 ( + ) T cells and MDA5 results in CD8 ( + ) T cell exhaustion and persistent infection ... In the absence of MDA5, CD8 ( + ) T cell responses to acute infection rely on CD4 ( + ) T cell help, and loss of both CD4 ( + ) T cells and MDA5 results in CD8 ( + ) T cell exhaustion and persistent infection