Gene interactions and pathways from curated databases and text-mining

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CXCL10 — IL6

Text-mined interactions from Literome

Punturieri et al., J Immunol 2006 : Synthetic OMP elicited strong release of IL-6 , the principal inducer of airway mucin genes, and induced CCL5 and CXCL10 from murine AMphi only when IFN-beta was also present
Hosokawa et al., J Periodontal Res 2009 (Periodontitis) : However, interleukin-4 and interleukin-13 inhibited CXCL10 production by interferon-gamma stimulated or tumor necrosis factor-alpha-stimulated-human gingival fibroblasts ... On the other hand, interleukin-17A and interleukin-22 enhanced CXCL10 production by human gingival fibroblasts treated with interferon-gamma and inhibited CXCL10 production by tumor necrosis factor-alpha stimulated human gingival fibroblasts
Lai et al., Int J Gynecol Cancer 2011 (Genital Neoplasms, Female...) : Similar treatment in HeLa cells caused increases in the mRNA levels of CCL2, CXCL2 , IL-6, and IL-8, and in SKOV3 cells, mRNA levels of CCL2, CCL20, CXCL1, CXCL2, IL-6 , and IL-8 increased
Tousi et al., Neurosci Lett 2012 (Parkinson Disease) : a-Synuclein potentiates interleukin-1ß induced CXCL10 expression in human A172 astrocytoma cells
Lam et al., Virology journal 2011 (Influenza in Birds...) : The results showed that CXCL-10/IP10 was most prominently induced ( > 1000 folds ) and IL-6 was slightly induced ( < 10 folds ) by all subtypes
Lee et al., J Immunol 2012 : CCR1 mediated STAT3 tyrosine phosphorylation and CXCL8 expression in THP-1 macrophage-like cells involve pertussis toxin-insensitive Ga ( 14/16 ) signaling and IL-6 release