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CORIN — NPPA
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Yan et al., Proc Natl Acad Sci U S A 2000
:
Our findings suggest that corin is the long-sought pro-ANP converting enzyme and that the
corin mediated
pro-ANP activation may play a role in regulating blood pressure
Hooper et al., Eur J Biochem 2000
(Heart Diseases...) :
In in vitro experiments, recombinant human
corin has recently been shown to
activate pro-atrial natriuretic peptide (ANP) , a cardiac hormone essential for the regulation of blood pressure
Wu et al., Cancer Res 2003
(Carcinoma, Small Cell...) :
In this study, we examined the
role of
corin in
ANP production by SCLC cells
Klein et al., Kidney Int 2010
(Nephrotic Syndrome) :
The serine/threonine protease
corin , which proteolytically
activates atrial natriuretic peptide (ANP) , is reduced in the kidneys of animals with nephrotic syndrome and glomerular nephritis