Billich et al., Int J Biochem Cell Biol 2009
:
Using selective stimulation of proteinase activated receptors (PARs) a specific involvement of SPHK1 in the PAR-1 induced responses in A549 cell, including activation of NFkappaB, was evident, while PAR-2 and PAR-4 responses were independent of SPHK1 Böhm et al., Cardiovasc Res 2013
:
FXa stimulated transcription of SPHK1 was mediated by the protease activated receptor-1 (PAR-1) and PAR-2