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HLA-DRB1 — TNFRSF1A

Text-mined interactions from Literome

Chen et al., Cancer Res 2003 (Breast Neoplasms) : Overexpression of a transdominant negative mutant of the inhibitory protein I kappa B alpha results in down-regulation of constitutively active NF-kappa B, induction of DR5 , and tumor necrosis factor receptor (TNFR) 1-associated death domain expression and enhancement of TRAIL sensitivity
Saqr et al., J Neuropathol Exp Neurol 2006 (Glioma) : We report here that death receptor-5 (DR5) , tumor necrosis factor receptor-1 ( TNF-R1 ), and Fas receptor (FasR) are all located in the caveolin-1 enriched membrane fractions, and TRAIL caused the translocation of DR5, FasR, and TNF-R1 to the caveolar fractions
Wosik et al., J Neurol Sci 2007 : TNFR1 ligation induces NFkappaB activation and the upregulation of chemokines MCP-1 and IL-8, as well as adhesion molecules ICAM-1 and VCAM-1, while Fas and DR5 triggering activate the extracellular signal regulated kinases-1 and -2 ( Erk 1/2, p42/44 MAPK ) inducing the release of matrix metalloproteinase 9 (MMP9) by BBB derived ECs