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CX3CL1 — NFKB1
Text-mined interactions from Literome
Brand et al., Gastroenterology 2002
(MAP Kinase Signaling System...) :
Fractalkine activated
NF-kappa B and p53 resulting in interleukin 8 and fractalkine mRNA expression
Depboylu et al., J Neuropathol Exp Neurol 2006
(Disease Models, Animal...) :
Treatment of AIDS monkeys with the central nervous system-permeant 6-chloro-2',3'-dideoxyguanosine fully reversed SIV burden, productive inflammation, nuclear
NF-kappaB translocation as well as focal
induction of
CX3CL1 in astrocytes and macrophages and downregulation in neurons
Popovic et al., J Leukoc Biol 2008
:
The thrombin induced
CX3CL1 expression was
NF-kappaB dependent , as shown by EMSA, ELISA, and by inhibition of the NF-kappaB signaling pathway by the IkappaB kinase inhibitor acety-11-keto-beta-boswellic acid or by transient overexpression of a transdominant negative form of IkappaBalpha
Gan et al., Cell Tissue Res 2013
(Inflammation) :
Inhibitors of p38MAPK, JAK-STAT,
NF-kB , and AP-1 significantly
reduced CX3CL1 and CX3CR1 expression