Gene interactions and pathways from curated databases and text-mining

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CD1D — CD8A

Text-mined interactions from Literome

Lee et al., Exp Mol Med 2009 : Although CD4 and CD8 coreceptors are not directly involved in the interaction between CD1d and the T cell receptors ( TCRs ) of iNKT cells, a conspicuous lack of CD8 ( + ) iNKT cells in mice raised the question of whether CD8 ( + ) iNKT cells are excluded due to negative selection during their thymic development, or if there is no lineage commitment for the development of murine CD8 ( + ) iNKT cells
Joshi et al., J Leukoc Biol 2012 : These results provide a clear demonstration that although CD1d expression on DCs is essential for NKT enhanced CD8 ( + ) T cell expansion, it is dispensable for specific antibody production