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GAD2 — IFNG

Text-mined interactions from Literome

Zanone et al., J Clin Endocrinol Metab 2010 (Diabetes Mellitus, Type 1) : Five diabetic patients were identified with a positive PBMC IFN-gamma response to GAD65 and negative IL-10 and IL-4 response
Tian et al., J Exp Med 1996 (Diabetes Mellitus, Type 1) : GAD65 peptide treated mice displayed greatly reduced IFN gamma responses and increased IL-5 responses to GAD65 , confirming the diversion of the spontaneous GAD65 Th1 response toward a Th2 phenotype
Hao et al., Autoimmunity 1995 : 3 ) IFN gamma at doses of 10, 100, 1000 U/ml had no effect on insulin secretion or on GAD-65 expression