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HOXA9 — KMT2A
Text-mined interactions from Literome
Kumar et al., Blood 2004
(Leukemia) :
Gene expression profiling revealed that expression of
Mll-AF9 led to overexpression of Hoxa5, Hoxa6, Hoxa7,
Hoxa9 , and Hoxa10
Wang et al., EMBO J 2005
(Myeloproliferative Disorders) :
Inhibition of Hox a9 expression by RNA interference demonstrated that
MLL-CBP required
Hox a9 for its enhanced cell expansion
Wang et al., Cell 2010
:
Furthermore, the
MLL1-CyP33 interaction is
required for repression of
HOXA9 and HOXC8 genes in vivo
Muntean et al., Cancer Cell 2010
(Cell Transformation, Neoplastic...) :
PAFc augments
MLL and MLL-AF9
mediated transcriptional activation of
Hoxa9