Gene interactions and pathways from curated databases and text-mining

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CRHR2 — LEP

Text-mined interactions from Literome

Proulx et al., Endocrinology 2002 (Weight Gain) : We conclude that despite adult-like effects of leptin on POMC, NPY, and CRFR-2 expression in neonates, leptin does not regulate food intake during early development
Makino et al., Am J Physiol 1998 (Starvation) : The concordance of a fall in plasma insulin and leptin levels with the fall in VMH CRHR-2 mRNA levels further supports the idea that compensatory responses during starvation and adrenalectomy include not only the disinhibiting effects of reduced insulin and leptin levels on appetite through already described mechanisms but also via an effect of leptin on VMH CRHR-2