Samarakoon et al., J Mol Cell Cardiol 2008
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Thus, two distinct pathways involving the EGFR/pp60(c-src)/MEK-ERK pathway and Rho/ROCK dependent SMAD2 activation are required for TGF-beta1 induced PAI-1 expression in VSMC
Lee et al., J Cell Sci 2010
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Src dependent phosphorylation of ROCK participates in regulation of focal adhesion dynamics ... Altogether, our data suggest that Src dependent ROCKII phosphorylation provides a means of tuning contractility required for FAs dynamics when RhoA is active