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CPOX — IL4

Text-mined interactions from Literome

Noguchi et al., Inflammation 1999 : IL-4 and IFN-gamma suppressed PGE2 production by IL-1beta stimulated PDL fibroblasts, but COX activity enhanced by IL-1beta treatment was significantly inhibited by IL-4 , not by IFN-gamma
Hayashi et al., Cytokine 2000 : The regulatory effects of interferon (IFN)-gamma and IL-4 on IL-1beta induced COX , PLA(2)isoforms expression and terminal delayed PGE ( 2 ) generation were examined in three types of human fibroblasts
Moore et al., J Appl Physiol 2001 : In human cultured airway smooth muscle cells, interleukin (IL)-1 beta increases cyclooxygenase (COX)-2 expression and PGE ( 2 ) release, ultimately resulting in decreased beta-adrenergic responsiveness
Saito et al., Int Arch Allergy Immunol 2003 (Fibrosis) : IL-4 and IL-13 stimulate fibroblast proliferation and this effect is at least partly due to suppressed COX gene expressions and subsequently decreased PGE ( 2 ) production
Helmersson et al., Free radical research 2005 (Cardiovascular Diseases...) : This study investigated the longitudinal association between serum selenium ( s-Se ) and a golden standard indicator of oxidative stress in vivo ( 8-iso-prostaglandin F2alpha, a major F2-isoprostane ), an indicator of cyclooxygenase (COX) mediated inflammation ( prostaglandin F2alpha ), high sensitive C-reactive protein ( hsCRP ), interleukin-6 (IL-6) and serum amyloid A protein (SAA) in a follow-up study of 27 years
Schwartzbaum et al., Cancer Epidemiol Biomarkers Prev 2007 (Genetic Predisposition to Disease...) : In addition, recent studies suggest that IL-4 and IL-13 induce cyclooxygenase-2 (COX-2) to resolve brain inflammation
Yao et al., Inflamm Res 2010 : Moreover, NF-kappaB p50, COX-2 , and iNOS levels in SF were markedly suppressed by AD-IL-18BP/IL-4
Obermajer et al., Transplantation research 2012 : We observed that PGE2 induces endogenous cyclooxygenase (COX)2 expression in cultured monocytes, blocking their differentiation into CD1a+ dendritic cells (DCs) and inducing the expression of indoleamine 2,3-dioxygenase 1, IL-4Ra , nitric oxide synthase 2 and IL-10 - typical MDSC associated suppressive factors
Niiro et al., Blood 1997 : Moreover, IL-10 and IL-4 inhibited LPS induced cyclooxygenase (COX) activity in neutrophils
Endo et al., Am J Respir Cell Mol Biol 1998 : Lipopolysaccharide (LPS) stimulated PGE2 synthesis and COX activity were suppressed significantly by IL-4 , but were not affected significantly by IL-10, IL-13, or IFN-gamma
Dean et al., J Biol Chem 1999 : We have previously shown that the pyridinyl imidazole SB 203580, which inhibits it, blocks the interleukin-1 induction of cyclooxygenase-2 (COX-2) and matrix metalloproteinase 1 and 3 mRNAs in fibroblasts