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IL4 — SYK

Text-mined interactions from Literome

Toyabe et al., Immunology 2001 (Severe Combined Immunodeficiency) : Inhibition of Syk by piceatannol resulted in decreased production of IL-4 and expression of CD40L on patient 's CD4+ T cells
Ratthé et al., J Leukoc Biol 2007 : We also demonstrated that IL-4 induced phosphorylation of Syk , p38, Erk-1/2, JNK, Jak-1, Jak-2, STAT6, and STAT1 and that treatment of cells with the inhibitors piceatannol, SB203580, PD98059, or AG490 reversed the ability of IL-4 to delay neutrophil apoptosis
Ennaciri et al., J Immunol 2009 : In this study, we demonstrate for the first time that Syk is constitutively associated with IL-4R(alpha)in human polymorphonuclear neutrophils ( PMNs ) and that IL-4 stimulation increases the amount of Syk associated with IL-4R(alpha)