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CALM3 — SP1
Text-mined interactions from Literome
Pan et al., J Lab Clin Med 2000
:
When pPac-Spl, pPac-Sp3, pPac-USp3, and pPac-Sp4 were cotransfected with rCaM 1-392 promoter into Drosophila SL2 cells and challenged with 10,000 microU/mL insulin, we discovered that ( 1 ) Sp1 enhanced both basal and insulin stimulated CaM I gene expression ; ( 2 ) USp3, a `` long '' form of the Sp3 molecule, had a stimulatory effect on CaM I gene expression ; ( 3 )
Sp1 or USp3 is involved in mediating insulin-stimulation of the CaM I gene in SL2 cells ; and ( 4 ) Sp3, a `` short '' form of the Sp3 molecule, and Sp4
inhibited Spl stimulated and insulin stimulated Sp1 mediated
CaM I gene expression
Solomon et al., Endocrinology 1997
:
Transcription factor Sp1 is
necessary for basal
calmodulin gene transcription and for its selective stimulation by insulin