Gene interactions and pathways from curated databases and text-mining

◀ Back to CALM3

CALM3 — SP1

Text-mined interactions from Literome

Pan et al., J Lab Clin Med 2000 : When pPac-Spl, pPac-Sp3, pPac-USp3, and pPac-Sp4 were cotransfected with rCaM 1-392 promoter into Drosophila SL2 cells and challenged with 10,000 microU/mL insulin, we discovered that ( 1 ) Sp1 enhanced both basal and insulin stimulated CaM I gene expression ; ( 2 ) USp3, a `` long '' form of the Sp3 molecule, had a stimulatory effect on CaM I gene expression ; ( 3 ) Sp1 or USp3 is involved in mediating insulin-stimulation of the CaM I gene in SL2 cells ; and ( 4 ) Sp3, a `` short '' form of the Sp3 molecule, and Sp4 inhibited Spl stimulated and insulin stimulated Sp1 mediated CaM I gene expression
Solomon et al., Endocrinology 1997 : Transcription factor Sp1 is necessary for basal calmodulin gene transcription and for its selective stimulation by insulin