Gulli et al., Mol Cell 2000
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Our results thus suggest a dynamic temporal and spatial regulation of the Cdc42 module : Cdc28-Cln triggers actin polarization by activating Cdc42 , which in turn restricts its own activation via a negative feedback loop acting on its GEF Cdc24
Rida et al., Eur J Cell Biol 2005
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It has been shown that the role of Cdc42 in bud emergence requires both Cdc28-Cln ( G1 ) kinase and the passage through START