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NOS2 — VCAM1

Text-mined interactions from Literome

Bayón et al., Br J Pharmacol 1999 : 6. These data indicate that the incorporation of a 4-trifluoromethyl group to the salicylate molecule strongly enhances its inhibitory effect on NF-kappaB activation, VCAM-1 mRNA expression and iNOS induction , irrespective of the presence of the acetyl moiety involved in the inhibition of cyclo-oxygenase
Kawachi et al., Am J Physiol 1999 (Chronic Disease...) : Role of inducible nitric oxide synthase in the regulation of VCAM-1 expression in gut inflammation ... We conclude that iNOS may regulate VCAM-1 expression in acute inflammation ; however, this effect is modest and tissue specific and occurs only when VCAM-1 expression is submaximal ... The objectives of this study were to assess the role of the inducible isoform of nitric oxide synthase (iNOS) on vascular cell adhesion molecule 1 ( VCAM-1 ) expression in vivo in an acute model of inflammation induced in iNOS-deficient (iNOS-/-) mice and compare these data to those obtained by pharmacological inhibition of iNOS in a CD4+ T lymphocyte dependent model of chronic colitis
Mikkelsen et al., Histochem Cell Biol 2008 (Inflammation...) : LPS induced VCAM-1 activation of the vessels, modest influx of granulocytes, as well as an iNOS-activation in a cell type different from macrophages in both +/+ and op/op mice
Bayat et al., Free Radic Biol Med 2012 : Activation of TPr also enhanced IL-1ß induced vascular cell adhesion molecule (VCAM)-1 expression, but inhibited inducible nitric oxide synthase (iNOS) expression
Peng et al., J Immunol 1998 (Inflammation) : Inhibition of iNO synthase (iNOS) activity with N omega-monomethyl-L-arginine in endothelial-RAW264.7 cocultures, stimulated with murine-specific IFN-gamma and LPS, decreased iNO production by 86 %, augmented VCAM-1 and iNOS expression in endothelial and RAW264.7 cells, respectively, and increased monocyte adhesion to the endothelial cell surface