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CCL2 — NOX1

Text-mined interactions from Literome

Brandes et al., Thromb Haemost 2001 (MAP Kinase Signaling System) : Thrombin induced MCP-1 expression involves activation of the p22phox containing NADPH oxidase in human vascular smooth muscle cells
Brandes et al., Antioxid Redox Signal 2003 : By influencing the activity of p38 mitogen activated protein kinase and AKT, NADPH oxidase derived O ( 2 ) .- increases the expression of several pro-arteriosclerotic genes, such as monocyte chemoattractant protein-1 , tissue factor, and vascular endothelial growth factor
Yamagishi et al., Drugs Exp Clin Res 2003 : Nifedipine inhibits tumor necrosis factor-alpha induced monocyte chemoattractant protein-1 overexpression by blocking NADPH oxidase mediated reactive oxygen species generation ... The results demonstrate that nifedipine could inhibit TNF-alpha induced MCP-1 overexpression in HUVEC by suppressing NADPH oxidase mediated ROS generation
Tölle et al., Arterioscler Thromb Vasc Biol 2008 : HDL associated lysosphingolipids inhibit NAD ( P ) H oxidase dependent monocyte chemoattractant protein-1 production
Turchan-Cholewo et al., Antioxid Redox Signal 2009 : Furthermore, inhibition of NADPH oxidase attenuated Tat induced release of interleukin-6 (IL-6), tumor necrosis factor alpha (TNF), and monocyte chemoattractant protein 1 ( MCP-1 ), and decreased microglial mediated neurotoxicity
Zhang et al., Nephrology (Carlton) 2009 : Role of NAD ( P ) H oxidase in transforming growth factor-beta1 induced monocyte chemoattractant protein-1 and interleukin-6 expression in rat renal tubular epithelial cells ... This study investigated the role of NAD ( P ) H oxidase in transforming growth factor-beta1 ( TGF-beta1 ) -induced reactive oxygen species ( ROS ) generation, monocyte chemoattractant protein-1 ( MCP-1 ), and interleukin-6 (IL-6) expression in rat renal tubular epithelial NRK-52E cells
Zhang et al., Invest Ophthalmol Vis Sci 2009 (Diabetes Mellitus, Experimental...) : NAD ( P ) H oxidase dependent regulation of CCL2 production during retinal inflammation ... In this study, the role of NAD ( P ) H oxidase in CCL2 production was assessed ... Analysis of downstream signals showed that inhibition of NAD ( P ) H oxidase partially inhibited NF-kappaB activation but did not reduce CCL2 mRNA stability or prevent TNF-alpha induced phosphorylation of p38MAPK ... NAD ( P ) H oxidase activity is required for CCL2 production during retinal vascular inflammation
Pan et al., Braz J Med Biol Res 2009 (Inflammation) : These data suggest that the inhibition of NAD ( P ) H oxidase dependent NF-kappaB signaling reduces the increase in MCP-1 production by GECs induced by Ang II
Chen et al., Zhonghua Bing Li Xue Za Zhi 2009 : NADPH oxidase derived ROS is involved in AngII induced MCP-1 expression
Lee et al., Inflamm Res 2010 : Role of NADPH oxidase in interleukin-4 induced monocyte chemoattractant protein-1 expression in vascular endothelium ... Additionally, pharmacological inhibitors of NADPH oxidase ( NOX ) significantly attenuated IL-4 induced MCP-1 expression in HAEC
Cho et al., Inflamm Res 2011 (Inflammation...) : To investigate whether NADPH oxidase induces MCP-1 expression and the activation of mitogen activated protein kinases ( MAPKs ) in H. pylori infected gastric epithelial cells ... Inhibiting NADPH oxidase by DPI suppresses H. pylori induced activation of MAPKs and MCP-1 expression in AGS cells
Weaver et al., Mol Cell Endocrinol 2012 (Diabetes Mellitus) : Inhibitors of NADPH oxidase, apocynin and diphenyleneiodonium, and a dual selective NOX1/4 inhibitor, blocked ROS generation ( p < 0.01 ) and induction of MCP-1 ( p < 0.05 ) by pro-inflammatory cytokines in beta cells ... Inhibitors of NADPH oxidase , apocynin and diphenyleneiodonium, and a dual selective NOX1/4 inhibitor, blocked ROS generation ( p < 0.01 ) and induction of MCP-1 ( p < 0.05 ) by pro-inflammatory cytokines in beta cells