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ARF6 — EGF
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Li et al., Cancer 2009
(Glioblastoma) :
However, the
role of
ARF6 in
EGF signaling is unknown ... To determine whether
EGF induces
ARF6 expression in human glioblastoma U87 cells through transcriptional regulation and EGFR activation, the levels of ARF6 were assayed in EGF treated U87 cells that were preincubated with a transcriptional inhibitor ( actinomycin D ) and an EGFR tyrosine kinase inhibitor ( PD153035 ), respectively ... Furthermore,
EGF stimulated
ARF6 expression in U87 cells in a dose dependent and time-dependant manner ... It is noteworthy that SP1 was essential for
EGF induced
ARF6 up-regulation ... : The results of the current study suggested that EGF
induced ARF6
expression plays a significant role in glioma cell proliferation
Hu et al., Exp Cell Res 2013
(Breast Neoplasms...) :
EGF increased
Arf6 activity, ERK phosphorylation, and uPAR expression in a time dependent manner
Taira et al., Nephron 1994
(Acute Kidney Injury) :
In summary, urinary immunoreactive
EGF levels decreased and renal EGF levels
increased in rats with HgCl2 induced
ARF