Gene interactions and pathways from curated databases and text-mining

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CREB5 — S100A12

Text-mined interactions from Literome

Seybold et al., J Neurosci 2003 : CGRP increased phosphorylated CREB immunoreactivity and CRE dependent transcription in neurons, indicating the involvement of the transcription factor CREB
Kawase et al., Am J Physiol Cell Physiol 2005 : CGRP acted as a significant agonist only upon ERK dephosphorylation, whereas this analog effectively antagonized CGRP induced cAMP production and phosphorylation of cAMP response element binding protein ( CREB ) and p38 MAPK ... Although it had no agonistic action when used alone, CGRP ( 8-37 ) potently blocked CGRP actions on cAMP, CREB , and p38 MAPK but had less of an effect on ERK