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RHOA — SRI

Text-mined interactions from Literome

Huang et al., J Biol Chem 2007 (Calcium Signaling) : Collectively, these results suggest the following : 1 ) interaction of Galpha(13) SRI with p115RhoGEF is required for G ( 13 ) -mediated RhoA activation in platelets ; 2 ) signaling through the G ( 13 ) pathway is critical for PAR1 mediated human platelet functional changes and low dose thrombin induced aggregation ; and 3 ) G ( 13 ) signaling elicits calcium mobilization in human platelets through a Rho kinase independent mechanism
Kanaho et al., J Lipid Mediat Cell Signal 1996 : Evidence provided includes the findings that : ( 1 ) the partially purified preparation of the PLD activating factor by subsequent column chromatographies contained a 22 kDa substrate for botulinum C3 exoenzyme ADP-ribosyltransferase ; ( 2 ) the 22 kDa protein strongly reacted with anti-RhoA antibody ; ( 3 ) the treatment of the partially purified PLD activating factor with C3 exoenzyme and NAD together, but not individually, significantly inhibited the PLD stimulating activity ; and ( 4 ) recombinant isoprenylated RhoA activated the PLD