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ICAM1 — NOX4

Text-mined interactions from Literome

Fan et al., J Biol Chem 2002 : Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells
Frey et al., J Biol Chem 2006 : Thus, PI3Kgamma lies upstream of PKCzeta in the endothelium, and its activation is crucial in signaling NADPH oxidase dependent oxidant production and subsequent NF-kappaB activation and ICAM-1 expression
Jo et al., Antioxid Redox Signal 2006 (Atherosclerosis...) : The NADPH oxidase activation by BMP4 then leads to ROS production, NF-kappaB activation, intercellular adhesion molecule 1 ( ICAM-1 ) expression, and subsequent increased monocyte adhesivity of endothelial cells ... The NADPH oxidase activation by BMP4 then leads to ROS production, NF-kappaB activation, intercellular adhesion molecule 1 ( ICAM-1 ) expression, and subsequent increased monocyte adhesivity of endothelial cells
Park et al., Cardiovasc Res 2006 (Bacterial Infections) : Downregulation of Nox4 by transfection of siRNA specific to Nox4 in HAECs resulted in a failure to induce reactive oxygen species ( ROS ) generation and subsequent expression of intercellular adhesion molecule-1 ( ICAM-1 ) and chemokines such as IL-8 and monocyte chemoattractant protein-1 ( MCP-1 ) in response to LPS
Collins-Underwood et al., Free Radic Biol Med 2008 : Pharmacologic and genetic inhibition of NADPH oxidase blocked the radiation mediated upregulation of intracellular ROS, activation of NFkappaB, and upregulation of ICAM-1 and PAI-1
Heo et al., Vascul Pharmacol 2010 (Atherosclerosis) : Furthermore, the NADPH oxidase assembly inhibitor, AEBSF, and the blocker of NADPH oxidase, p47(phox) small interference RNA ( siRNA ), also efficiently blocked LIGHT induced migration, CCR1, CCR2, ICAM-1 , and HVEM expression, and p38 MAPK and NF-kB activation ... Furthermore, the NADPH oxidase assembly inhibitor, AEBSF, and the blocker of NADPH oxidase, p47(phox) small interference RNA ( siRNA ), also efficiently blocked LIGHT induced migration, CCR1, CCR2, ICAM-1 , and HVEM expression, and p38 MAPK and NF-kB activation
Song et al., Free Radic Biol Med 2011 (AIDS Dementia Complex) : Nox2 based NADPH oxidase mediates HIV-1 Tat induced up-regulation of VCAM-1/ICAM-1 and subsequent monocyte adhesion in human astrocytes ... HIV-1 Tat induced up-regulation of VCAM-1/ICAM-1 and subsequent increased adhesion of monocytes to astrocytes were blocked by a general NADPH oxidase inhibitor, diphenylene iodonium, and a specific inhibitor of NADPH oxidase assembly, 9R3A-gp91ds
Menden et al., Am J Physiol Lung Cell Mol Physiol 2013 : LPS induced expression of intercellular adhesion molecule 1 ( ICAM-1 ) was associated with increased 2-OH-E ( + ) ( marker for superoxide formation ) levels and was attenuated by apocynin and the Nox inhibitor, VAS2870 ... Silencing Nox2 , but not Nox4, suppressed LPS induced ICAM-1 expression in HPMEC
Peshavariya et al., PloS one 2013 (Inflammation) : Inhibition of NADPH oxidase activity by either dominant negative Rac1 ( N17Rac1 ) or DPI significantly attenuated TNFa induced ICAM-1and VCAM-1 expression
Arai et al., Biochem J 1998 (Second Messenger Systems) : This ICAM-1 upregulation was also inhibited by inhibitors of NADH dehydrogenase, cytochrome bc1 complex and NADPH oxidase