Gene interactions and pathways from curated databases and text-mining

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GRAP2 — TNFRSF1A

Text-mined interactions from Literome

Brinkman et al., J Biol Chem 1999 : Engagement of tumor necrosis factor (TNF) receptor 1 leads to ATF-2- and p38 mitogen activated protein kinase dependent TNF-alpha gene expression
Itatsu et al., Liver Int 2009 (Cholangiocarcinoma) : These data suggest that TNF-alpha/TNF-R1 interaction leads to the phosphorylation of Erk1/2 and p38MAPK and nuclear translocation of NF-kappaB, which is closely associated with the production and activation of MMP-9 in cultured CC cells of HuCTT-1 and CCKS-1