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CASP3 — NOTCH1

Text-mined interactions from Literome

Yao et al., Dig Liver Dis 2009 (Stomach Neoplasms) : As the molecular mechanism involved, we showed over activated Notch-1 partially suppressed TNFalpha induced activation of caspase-3 ... Our data indicate that over activated Notch-1 significantly protects BGC-823 cells from TNFalpha induced apoptosis, and this effect is mediated , at least in part, by decreasing activation of caspase-3 independent of NF-kappaB
Garg et al., Gastroenterology 2011 (Colitis...) : Inhibition of Notch1 signaling significantly reduced protein levels of active Notch1, p53, p21WAF1/Cip1, Bax-1, active caspase-3 , as well as apoptosis, compared with controls