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ARF4 — INS

Text-mined interactions from Literome

Li et al., BMC cell biology 2003 : Here we tested the hypothesis that ARF-guanine nucleotide exchange factors ( ARF-GEFs ) of the cytohesin/ARNO family mediate the activation of ARF and PLD by insulin ... Wild type ARNO transiently transfected in HIRcB cells was translocated to the plasma membrane in an insulin dependent manner and promoted the translocation of ARF to the membranes
May et al., Kidney Int 1985 (Insulin Resistance...) : In the absence and presence of insulin , muscle protein degradation was increased by ARF
Karnam et al., J Biol Chem 1997 : Our findings suggest that : ( a ) insulin translocates Rho by a PI 3-kinase dependent mechanism, but another factor is responsible for GTP loading of Rho ; ( b ) both Rho and ARF may contribute to PC-PLD activation during insulin action ; and ( c ) Rho may be required for insulin stimulation of glucose transport
Shome et al., Curr Biol 1997 : We found that in membranes obtained from HIRcB cells, a cell line derived from Rat-1 fibroblasts that overexpresses normal human insulin receptors, binding of the GTP analogue GTPgammaS to purified bovine or recombinant ARF was enhanced in the presence of insulin ... The activation of ARF proteins is stimulated by insulin and this process plays an important role in insulin mediated regulation of PLD